Tag: COVID-19

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Heart damage: Another reason to cut down on children’s screen time

Heart damage: Another reason to cut down on children’s screen time

Evidence indicates that excessive screen time is harmful both to neurological development and socialisation.

The effects of prolonged screen use during childhood have been extensively studied in recent years. Evidence indicates that excessive screen time is harmful both to neurological development and socialisation. This is because, among other things, they cause us to disconnect from our surroundings, leading to very real addictions that often require intervention from a mental health professional.

Additionally, screen use can cause neurocognitive learning disorders at the early stages of personality formation in childhood.

But above all, excessive time spent in front of televisions, video games, mobile phones and tablets during childhood and adolescence leads to a sedentary lifestyle.

In fact, there is already a proven link between overuse of screens and the increase in sedentary lifestyles among children.

Now, a new dimension can be added to all these reasons for limiting the time children spend in front of televisions, video games and mobile phones.

According to a new study, led by Andrew Agbaje at the University of Eastern Finland in Kuopio and presented at the European Society of Cardiology Congress 2023, sedentary children are at increased risk of heart damage in early adulthood.

Heart damage: Another reason to cut down on children’s screen time

In other words, inactivity during infancy may well set the stage for heart attacks and strokes later in life, even if weight and blood pressure are within the normal ranges.

Excessive screen time increases heart weight

The research analysed the cumulative effects of sedentary time on the heart, drawing data from Children of the 90s, a landmark multigenerational study that is unique in its breadth and depth of scope.

It tracked the health and lifestyles of 14,500 babies born in 1990 and 1991 into their adult lives.

Of the children included in the study, 766 –55 per cent of them girls and 45 per cent boys– were asked at age 11 to wear a smart watch that monitored their activity for seven days.

At age 15 they were asked to repeat this, and then again at 24. In parallel, an echocardiographical analysis was taken of each subject’s left ventricle at ages 17 and 24, which was then adjusted for height, sex, blood pressure, body fat, tobacco use, physical activity and socioeconomic status.

The results indicated that at age 11 the subjects were sedentary for an average of 362 minutes per day.

In adolescence (age 15) this increased to 474 minutes per day, and then went up to 531 minutes per day in adulthood (age 24).

Sedentary time increased by an average of 2.8 hours per day over the 13 years of the study.

A large amount of this sedentary time was spent in front of screens. `Most seriously, the echocardiography registered an increase in heart weight among young people that correlated directly to time spent being sedentary.

Once they entered adulthood, this increased the likelihood of heart attacks and strokes.

This direct relation between accumulated inactive time and heart damage was independent of body weight and blood pressure.

Tell me how much you moved as a child…

By now it is common knowledge that sedentary lifestyles increase the risk of metabolic conditions (such as obesity and type 2 diabetes), neurodegenerative disease and cardiovascular disease in adults.

The new study shows that sedentary behaviour at a very early age –especially unrestricted screen time– may lead to an earlier onset of cardiovascular disease in adulthood.

For this reason, it is of the utmost importance that parents encourage children and adolescents to move around more, and limit the time they spend watching television, or using social media and videogames.

As we have already suggested with regard to premature birth, the list of known, conventional cardiovascular risk factors (smoking, diabetes, hypertension, etc.) should be revised and updated as a result of the study to include the cumulative time spent engaging in sedentary behaviour in childhood.

We should all, from an early age, heed the words of Martin Luther King when he said “If you can’t fly, then run. If you can’t run, then walk. If you can’t walk, then crawl, but whatever you do, you have to keep moving.”

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COVID-19 Medical Equipments Medical Updates

Covid-19 antibodies making dengue more severe, says study; what experts say

Covid-19 antibodies making dengue more severe, says study; what experts say

As per a new study, Covid-19 antibodies can cross-react with DENV-2 and can worsen dengue infection. Here’re possible reasons why this may be happening.

While the rise in number of dengue cases in India is being attributed to heavy rains and waterlogging in many areas, Covid-19 antibodies may have been adding to the vector-borne disease’s severity, according to a new study. The analysis titled ‘SARS-CoV-2 antibodies cross-react and enhance dengue infection’ has been done at the Translational Health Science and Technology Institute (THSTI) under the central government’s department of biotechnology; the yet-to-be peer-reviewed study has been published in bioRxiv, the preprint server for medical sciences.

“This study is the first to demonstrate that anti-SARS-CoV-2 antibodies can cross-react with DENV-2 (dengue virus 2) and can enhance its infection through antibody- dependent enhancement (the ability of antibodies from a previous infection to help a virus infect greater numbers of cells than it would have on its own),” it said.

Dr Harish Chafle, Extensive experience in Pulmonology and Critical Care, Global Hospitals Parel Mumbai offers insights into the potential link between Covid-19 antibodies and worsening dengue cases.

Covid-19 antibodies making dengue more severe, says study; what experts say

“As we delve into the complex interactions of viral infections, we must consider the possibility of cross-reactivity between Covid-19 antibodies and dengue. The human immune system is a highly intricate network, and sometimes, antibodies produced in response to one virus can influence the body’s response to another. In the case of Covid-19 antibodies and dengue, it’s crucial to investigate if the presence of Covid-19 antibodies may inadvertently enhance the severity of dengue infection. This phenomenon is not entirely unexpected, as such interactions have been observed in other viral co-infections. The key lies in understanding the specific mechanisms at play, and whether these interactions can be harnessed for therapeutic strategies or if precautions should be taken for individuals at risk for both infections. More research is needed to shed light on this intricate relationship and its implications for public health,” says Dr Chafle.

Dr. Aditya S Chowti, Senior consultant, Internal Medicine, Fortis Cunningham, Bengaluru says there are several plausible explanations for how Covid-19 antibodies might exacerbate dengue infection:

1. Antibody-dependent enhancement (ADE) is a possibility where Covid-19 antibodies attach to dengue viruses without neutralizing them, potentially aiding the viruses in entering cells more effectively.

2. Another scenario involves Covid-19 antibodies triggering an exaggerated immune response, causing inflammation and tissue damage, which can intensify dengue symptoms.

3. Covid-19 infection might weaken the immune system, rendering individuals more susceptible to dengue and increasing the likelihood of severe disease.

“Further research is essential to comprehensively comprehend these mechanisms. It is crucial to acknowledge this potential risk, particularly for those who have had Covid-19 in dengue-endemic regions. In the interim, individuals should take steps to safeguard themselves against both Covid-19 and dengue, such as receiving the Covid-19 vaccine and practicing mosquito bite prevention, like using insect repellent and wearing protective clothing when outdoors,” adds Dr Chowti.

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Medical Updates Medicine & Health

7 signs of poor mental health you shouldn’t ignore

7 signs of poor mental health you shouldn't ignore

Poor mental health can take a heavy toll on physical health and may even lead to serious ailments and chronic health issues.

Poor mental health can directly affect your productivity, moods and relationships. If not addressed, it can put one at risk of mental health disorders. Unlike other illnesses, signs of mental health issues are not clear but some of the early signs of poor mental health are disrupted sleep, sullen mood and irritable behavior. Poor mental health can take a heavy toll on physical health and may even lead to serious ailments and chronic health issues. Like other aspects of health, our mental health also requires attention. If you are finding it difficult to focus, facing sleep issues, suffering from aches and pains or isolating yourself, you must consult a mental health expert to get into the root of your problems.

“Mental health encompasses an individual’s emotional, psychological, and social well-being, shaping their thoughts, emotions, and behaviors. Therefore, it is essential for individuals to remain vigilant for signs that could indicate a decline in their mental well-being. Some of these signs include lack of proper refreshing sleep, sustained mood change, significant changes in energy levels, losing interest, feeling quite insecure, odd experiences of hearing or seeing things that others cannot, thinking of harming self, and losing the meaning of life, sometimes accompanied by aggression,” says Dr Sameer Malhotra, Director and Head – Department of Mental Health and Behavioral Sciences, Max Super Specialist Hospital, Saket.

7 signs of poor mental health you shouldn't ignore

“Our mental health is as important as physical health, and recognizing the signs of struggling mental well-being is crucial for early intervention and support,” says Dr Jyoti Kapoor, Founder-Director and Senior Psychiatrist, Manasthali

Here are 7 poor mental health signs shares by Dr Jyoti Kapoor that one should never ignore:

1. Persistent mood swings: Feeling consistently sad, hopeless, or experiencing drastic mood swings that interfere with daily life can be a sign of depression or other mood disorders.

2. Social withdrawal: If you start isolating yourself, avoiding friends and family, it may indicate emotional distress or social anxiety.

3. Irregular sleeping patterns: Insomnia, oversleeping, or disrupted sleep can be linked to mental health issues.

4. Appetite and weight changes: Significant changes in appetite, whether overeating or undereating, can be indicative of emotional distress.

5. Difficulty in concentrating: Struggling to focus, making decisions, or complete tasks may be a sign of underlying mental health issues, such as anxiety or attention disorders.

6. Constant aches: Unexplained physical symptoms like headaches, stomach aches, or unexplained aches and pains can sometimes be manifestations of emotional distress.

7. Increased substance use: Escalating or excessive use of alcohol, drugs, or other substances as a coping mechanism can be a red flag for mental health problems.

If you or someone you know is exhibiting these signs, please reach out to a mental health professional or a counsellor.

Read more at-https://shorturl.at/aTXZ6

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Government Guidelines Medical Updates Medicine & Health

Long Covid patients are much more likely to have multiple organ abnormalities

Long Covid patients are much more likely to have multiple organ abnormalities

MRI scans revealed that people with long COVID were 14 times more likely to have lung abnormalities than people who never had the disease.

It wasn’t that long ago that some people speculated that long COVID was all in the mind – a psychosomatic illness. Thankfully, that period of speculation is now behind us. We have compelling evidence that long COVID is very real and very harmful. I’m the lead investigator on an ongoing study called C-More which looks at the long-term harms caused by COVID.

People with long COVID who had abnormalities involving more than two organs were four times more likely to report “severe” or “very severe” mental and physical impairment.

In the beginning

When COVID first emerged, doctors perceived it to be a respiratory illness, with patients reporting pronounced coughing, shortness of breath and symptoms akin to pneumonia.

But as our global understanding of the disease evolved, so did our appreciation of this complex disease.

Reports began to emerge that the virus was capable of not just affecting the lungs but also other organs, such as the heart, kidneys, brain and blood vessels, causing a broader assault.

Studies identifying the viral proteins in various organs also began to emerge, demonstrating the virus’s fondness for certain tissues that were not part of the lungs.

Originally, the main theory put forward was that SARS-CoV-2 (the virus that causes COVID) was directly infecting cells across multiple organs.

But, as data accumulated, a more nuanced understanding emerged. It was observed that in some patients, the immune system, in its defence against the virus, overshot its response, leading to what’s termed a “cytokine storm”.

This hyperactive immune reaction wasn’t always discriminative, causing unintended damage to organs not directly under viral attack.

Further reports highlighting the predisposition of the virus to induce excess clotting, mitochondrial disruption (mitochondria being the powerhouses of our cells) and reactivation of other viruses emerged.

Long Covid patients are much more likely to have multiple organ abnormalities

More importantly, there was a growing number of patients continuing to report persistent disabling symptoms arising from multiple organs, even after surviving the initial infection, also known as long COVID, a condition now thought to affect one in ten people.

So the narrative shifted. COVID wasn’t merely a short respiratory affliction, but a multisystem disease with the potential for long-term complications, challenging our assumptions about how to treat the disease.

The birth of C-More

To shed light on these questions, the C-More study was launched in the UK, focusing on the after-effects of the virus in patients who had been hospitalized.

Few studies on long COVID have looked at multiple organ harm in the same patient. And those that have, have tended to focus on patients who weren’t hospitalized with COVID.

This makes our study unique. However, as with any pioneering study, there are some limitations.

The latest results, mentioned above, are based on preliminary data (interim analysis from half the study population). A complete analysis is still awaited.

Pre-COVID MRI scans from patients were not available, making definitive conclusions about the link between COVID and the organ changes difficult.

The control participants were not an exact match to the patient population, but we adjusted our analyses to account for any differences, ensuring the findings were as accurate as possible.

The MRI scans didn’t always explain the symptoms experienced in individual organs.

For instance, even if the MRI showed an organ to be normal, a patient could still exhibit related symptoms. The only strong tie identified was between lung abnormalities and chest tightness.

Still, this study was an important effort to better understand the long-term effects of COVID on multiple organ health.

It reminds us to be vigilant of the potential for long-term consequences of the disease and the importance of vaccination – particularly in people at risk of severe infections.

Doctors and healthcare services around the world can now refine follow-up care, with a focus on lung, brain, kidney and blood vessel health among patients recovering from serious COVID infections, based on our study’s results.

Read more at-https://shorturl.at/ewIZ9
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Medical Equipments Medical Updates Medicine & Health

Increasing daily steps by 3,000 can reduce blood pressure in older adults

Increasing daily steps by 3,000 can reduce blood pressure in older adults

The study explores how 3000 daily steps can help in regulating blood pressure in older adults.

A new study discovered that increasing exercise by 3,000 steps per day can significantly reduce high blood pressure in older persons.

Pescatello worked in Duck-Chun Lee’s lab at Iowa State University with Elizabeth Lefferts, the paper’s primary author, and others.

The findings were published in the Journal of Cardiovascular Development and Disease.

“We’ll all get high blood pressure if we live long enough, at least in this country,” Pescatello said. “That’s how prevalent it is.”

Pescatello is an expert on hypertension (the clinical term for high blood pressure) and exercise. Her previous research has demonstrated that exercise can have a significant immediate and long-lasting impact on lowering blood pressure in hypertensive adults.

This study sought to determine if older adults with hypertension could receive these benefits by moderately increasing their daily walking, which is one of the easiest and most popular forms of physical activity for this population.

It’s easy to do, they don’t need any equipment, they can do it anywhere at almost any time,” Lee said.

The study focused on a group of sedentary older adults between ages 68 and 78 who walked an average of about 4,000 steps per day before the study.

After consulting existing studies, Lee determined that 3,000 steps would be a reasonable goal. This would also put most participants at 7,000 daily steps, in line with the American College of Sports Medicine’s recommendation.

“3,000 steps is large enough but not too challenging to achieve for health benefits,” Lee said.

The team conducted the study during the height of the COVID-19 pandemic, which meant they had to do everything remotely.

The researchers sent participants a kit with pedometers, blood pressure monitors, and step diaries for participants to log how much they were walking each day.

Increasing daily steps by 3,000 can reduce blood pressure in older adults

On average, participants’ systolic and diastolic blood pressure decreased by an average of seven and four points, respectively, after the intervention.

“It’s exciting that a simple lifestyle intervention can be just as effective as structured exercise and some medications,” Lefferts saud.

The findings suggest that the 7,000-step regimen the participants in the study achieved is on-par with reductions seen with anti-hypertensive medications. Eight of the 21 participants were already on anti-hypertensive medications. Those participants still saw improvements in systolic blood pressure from increasing their daily activity.

“In a previous study, we found that when exercise is combined with medication, exercise bolsters the effects of blood pressure medication alone,” Pescatello said. “It just speaks to the value of exercise as anti-hypertensive therapy. It’s not to negate the effects of medication at all, but it’s part of the treatment arsenal.”

The researchers found that walking speed and walking in continuous bouts did not matter as much as simply increasing total steps.

“We saw that the volume of physical activity is what’s really important here, not the intensity,” Pescatello said.

“Using the volume as a target, whatever fits in and whatever works convey health benefits.”

Read more at-https://shorturl.at/ekmF5

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COVID-19 Government Guidelines Medical Updates Medicine & Health

‘Disease X’ could be 20 times deadlier than COVID-19, says expert

'Disease X' could be 20 times deadlier than COVID-19, says expert

UK healthcare professionals are preparing for a potential new pandemic known as ‘Disease X,’ which could be more deadly than COVID-19, with the capacity to result in 20 times more fatalities. Disease X could potentially cause up to 50 million deaths.

As COVID-19 transitions into a recurring and more familiar health concern, healthcare professionals in the UK are now gearing up for a potential new pandemic known as “Disease X.” They caution that this new virus could have a similar impact to the devastating Spanish Flu of 1918-1920.

Health experts are sounding the alarm about “Disease X,” a term coined by the World Health Organization. They warn that this potential new pandemic has the capacity to result in 20 times more fatalities than the coronavirus. The COVID-19 pandemic began in 2020 and has tragically claimed the lives of over 2.5 million people worldwide. Here are the top 10 points about Disease X.

1. In an interview with the Daily Mail, Kate Bingham, who served as the chair of the UK’s Vaccine Taskforce from May to December 2020, expressed her belief that Disease X is expected to be considerably more perilous than COVID-19.

 

2. Based on expert estimates, Disease X could potentially result in up to 50 million fatalities. “Let me put it this way: the 1918-19 flu pandemic killed at least 50 million people worldwide, twice as many as were killed in World War I. Today, we could expect a similar death toll from one of the many viruses that already exist,” she told the Daily Mail.

In response to Disease X, Bingham asserted, “the world will have to prepare for mass vaccination drives and deliver the doses in record time.”

'Disease X' could be 20 times deadlier than COVID-19, says expert

3. She disclosed that while scientists have identified 25 virus families encompassing thousands of individual viruses, she holds the view that there are millions of viruses yet to be discovered, and these have the potential to evolve into pandemics.

4. “In a sense, we got lucky with Covid-19, despite the fact that it caused 20 million or more deaths across the world. The point is that the vast majority of people infected with the virus managed to recover. Imagine Disease X is as infectious as measles with the fatality rate of Ebola [67%]. Somewhere in the world, it’s replicating, and sooner or later, somebody will start feeling sick.”

5. The rise in outbreaks, according to Bingham, is attributed to the growing trend of more people congregating in urban areas. She also emphasizes that the continual destruction of millions of acres of natural habitat each year is contributing to this increase.

6. “This reason is particularly important, because around three-quarters of emerging infectious diseases originate in animals and then leap from species to species until they can, in certain circumstances, infect human beings.”

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7. According to Bingham, one of the initial actions that need to be taken is to allocate the necessary financial resources, essentially putting “the money on the table.” Bingham said, ” The monetary cost of inaction is seismic. After all, even Covid-19 – a milder virus than Disease X – managed to leave us holding a bill for $16 trillion in both lost output and public health expenditure.”

8. Regarding vaccines for Disease X, there are currently no approved vaccines available. Nevertheless, Bingham underscores the importance of scientists developing a collection of “different prototype vaccines for every threatening virus family”. She stressed that only a ‘head start’ on vaccines could help to target specific features of Disease X.

9. Bingham explained about the portfolio strategy – vaccines countering different facets of the virus. She explains by saying that ‘different types of vaccines stimulate different immune responses and therefore they provide different levels of protection’.

10. She further noted that the manufacturing capabilities vary enormously across countries and regions. Some vaccine formats may be suitable for large-scale production, while others may be easier to produce in the third world. Third, we need to address the shortcomings of current vaccines, not all of which are durable, easy to transport or cheap. Fourth, researchers must be encouraged to trial new technologies and approaches to vaccine design, potentially leading to more effective and efficient vaccines in the future.”

Read more at-https://shorturl.at/einQ3

 

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COVID-19 Government Guidelines Medical Equipments Medical Updates

Immune cells are critical to efficacy of coronavirus vaccinations: Study

Immune cells are critical to efficacy of coronavirus vaccinations: Study

The study shows that vital subset of immune system cells that are required for successful vaccination of covid.

A study has provided fresh information on a vital subset of immune system cells required for successful vaccination against the SARS-CoV-2 pandemic virus.

The study, led by researchers at NYU Grossman School of Medicine and the New York Genome Centre, focused on T cells, which, along with B cells, form the human immune system’s response to invading viruses and bacteria. T lymphocytes labelled with the surface protein CD8 generate chemicals that kill infected cells directly. B cells secrete antibodies, which neutralise and mark contaminated cells for removal from the body.’

Vaccines expose patients to a bit of an invading bacterium in order to generate responses such as B and T cell activation so that the system is ready for the invader if it is met again. The COVID-19 mRNA vaccines were based on RNA, a genetic material utilised to encode the spike protein required by the virus to adhere to human cells. When mRNA instructions are injected, the spike is generated, and the immune response is activated.

In the rush to create vaccines against SARS-CoV-2, clinical trials relied mostly on antibody levels, when efficient diagnostics were available, to determine whether patients’ immune responses to mRNA vaccine candidates were protective. However, clinical protection was observed as early as ten days following the initial vaccine dose, well before neutralising antibodies could be produced. T cells were thought to be at least as significant in this protection, but normal methods for tracking them were too sluggish, so careful examinations of CD8 T cell responses were put on hold.

Immune cells are critical to efficacy of coronavirus vaccinations: Study

The study published in Nature Immunology describes a quick (high-throughput) approach for tracking T cell responses, demonstrates that they are critical to the early protection afforded by mRNA vaccines against COVID-19, and identifies the T cell subsets most responsible for it.

Our study identified markers for the CD8 T cells that arise from mRNA vaccination and that track closely with successful vaccination, which had previously been difficult to quantify on the population level,” said co-first study author Rabi Upadhyay, MD, assistant professor in the Department of Medicine at NYU Langone Health, and faculty in its Perlmutter Cancer Center.

“Although our study looks at mRNA vaccination against coronavirus, the antigen-specific CD8 T cell subpopulations we uncover represent key features of immune responses more broadly, and may help us to study T cells in other disease settings.”

For the current study, the research team analyzed gene expression over time in single T cells collected before and after immunization with the mRNA vaccine produced by BioNTech and Pfizer against SARS-CoV-2.

The researchers found distinct subsets of CD8 T cells that reliably multiplied (proliferated) 21 days after the original vaccination, specifically targeting and attacking key proteins (antigens) that make up the pandemic virus.

In looking at the genetic makeup of the most effective T cells, the researchers observed that cells lacking a surface protein called KLRG1, which stands for co-inhibitory receptor killer-cell lectin-like receptor G1, were the most likely to multiply quickly after mRNA vaccination and specifically attack.

When study authors checked for these profiles in hospitalized COVID-19 patients, those with the most “properly programmed” T cells – lacking KLRG1 but expressing other markers such as CD38 and HLA-DR – were the most likely to successfully recover from their infections.

In the years since the pandemic began, mRNA vaccines, first used against the virus, are now in clinical trials wherein they direct the body’s immune system to attack cancerous cells.

By clarifying T cell markers (e.g. KLRG1, CD38, HLA-DR), and the timeline for when CD8 T cells arise in the blood after vaccination, the new work may enable clinical teams to tell which patients are responding to the vaccines within days or weeks, say the authors.

That compares to the more than two months that oncologists must currently wait after mRNA vaccination to perform CT scans and assess whether their lung, breast, or prostate cancer patients responded to an mRNA vaccine.

If they are validated in this setting and dramatically shorten such wait times, the new profiling methods promise to help patients pivot more quickly to other treatments if necessary, the researchers say.

Furthermore, the study authors refer to a recent study led by a different research team which found that T cells with very similar attributes, again involving KLRG1, CD38, and HLA-DR, were the most effective at attacking cancer cells after treatment with an immune system-triggering drug (immunotherapy), just as they were the most effective at attacking the SARS-CoV-2 virus in the current study.

“It is remarkable that T cell attributes found after treatment with an effective immunotherapy mirrored those that we found to track with patient recovery from COVID-19,” said co-corresponding author Dan Littman, MD, PhD, the Helen L. and Martin S. Kimmel Professor of Molecular Immunology in the Department of Cell Biology at NYU Langone. “This pattern suggests that the close monitoring of antigen-specific CD8 T cell subpopulations will be central to future efforts to design treatments and vaccines against either viruses or tumours.”

Read more at-https://shorturl.at/HKRY1

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COVID-19 Medical Updates Medicine & Health

Tips to unlock your happy hormones and move from stressed to calm

Tips to unlock your happy hormones and move from stressed to calm

From releasing emotions to stretching exercises, here are a few ways to unlock happy hormones.

Often, we feel that we are moving from one stressful experience to another. This can be extremely mentally draining and frustrating, and it can make us feel clueless about what to do next. Stress can impact the body and make us feel tired all the time. In such times, it is important to make conscious efforts to unlock the happy hormones that will help us see the positive. “Consciously remembering and reintroducing the things that used to make you smile and give you joy. Bringing in ways to help you relax and feel safe which will help you sleep,” wrote Psychotherapist Nikola Jack as she explained the importance of moving from stress with the help of happy hormones.

“After an unpleasant or stressful experience prioritising comfort, releasing stress hormones to make way for happy hormones can help us switch from stressed to calm,” added Nikola. She further suggested a few ways by which we can unlock the happy hormones:

Tips to unlock your happy hormones and move from stressed to calm

Releasing emotions: Be it talking about it to loved ones, or going for a walk to shake things off, or maintaining a journal of thoughts, we should find ways to release pent-up emotions and seek ways to release them in a healthy way.

Get warm and cozy: Wearing comfortable pajamas and getting inside a weighted blanket will help us feel that we are safe and happy in the environment. This will help us to further combat signs of stress.

Do the things you love: We all have a list of things that we love doing – be it painting, singing, dancing or just sitting and watching our favourite comfort movies all over again. Sometimes spending time with our pets and lying down while cuddling them can also make us happy.

Breathe and stretch: Doing stretching exercises such as the Child’s Pose, or Box Breathing, or meditation can help in having a better perspective on things.

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COVID-19 Medical Equipments Medical Updates Medicine & Health

Older adults with COPD had depression during COVID pandemic: Study

Older adults with COPD had depression during COVID pandemic: Study

According to a new longitudinal study published online in the International Journal of Chronic Obstructive Pulmonary Disease (COPD), older persons with COPD were at a higher risk of depression during the early phases of the COVID-19 epidemic

The study looked at 875 people with COPD from the Canadian Longitudinal Study on Ageing, a national study of Canadian seniors. Using longitudinal data, researchers were able to distinguish between 369 COPD patients who had a history of depression previous to the pandemic and 506 patients who had never experienced depression prior to the pandemic.

Researchers discovered that 1 in 6 people with COPD who had no prior history of depression experienced depression for the first time during the early phases of the pandemic. These findings show the toll that the epidemic inflicted on many people who had previously been depression-free.

“Our findings highlight the substantial burden of COVID-19 on those who were mentally healthy prior to the pandemic,” said first author Aneisha Taunque, research assistant at the Institute for Life Course and Aging at the University of Toronto. “It is evident that the pandemic has had a detrimental impact on the mental health of many individuals, even those who had no lifetime history of depression.”

When the analysis was restricted to those who had a history of depression prior to the pandemic, the prevalence of depression was substantially higher, with approximately one-half of these individuals experiencing a recurrence or persistence of depression during the autumn of 2020.

Older adults with COPD had depression during COVID pandemic: Study

“Older adults who have a history of depressive episodes are a highly vulnerable subset of the population, particularly those who faced numerous challenges with managing their chronic health conditions during the pandemic when access to regular health care was severely disrupted,” said co-author Grace Li, PhD candidate in the Sociology Department at the University of Victoria.

“The COVID-19 pandemic further exacerbated the risk of depression among those with COPD,” says co-author Ishnaa Gulati, a Master of Public Health Student at the University of Toronto’s Dalla Lana School of Public Health. “There was already an established higher risk of depression among individuals with COPD when compared to those without COPD prior to the pandemic,” Gulati said. “When considering the mental health stressors during the pandemic, such as extended periods of lockdown, economic precarity, and concerns about contracting or spreading COVID-19, it is unsurprising that this group experienced major mental health challenges during this period.”

Although there is a burgeoning body of research examining depression during the pandemic, very little research has specifically examined the vulnerabilities among those with COPD. Understanding the risk factors for depression in subpopulations of older adults can aid health professionals in more effectively targeting treatment.

The study’s researchers highlighted several risk factors for both incident and recurrent depression among those with COPD, including loneliness, family conflict, and functional limitations.

“We found that experiencing functional limitations approximately doubled the risk of depression among older adults with COPD,” said co-author Ying Jiang, Senior Epidemiologist at the Public Health Agency of Canada.

“Physical activity is integral for maintaining functional status and reducing functional limitations among COPD patients, however many individuals with COPD are hesitant to engage in physical activity. Increases in time spent sedentary during periods of lockdown may have further ramifications for this population, potentially contributing to increases in depression.”

Women with COPD also had nearly double the risk of recurrent depression when compared to their male counterparts.

“During the pandemic, many women experienced an exacerbation of gendered roles, such as increased time spent caregiving and doing household labour, which may have contributed to declines in their mental health,” said co-author Margaret de Groh, Scientific Manager at the Public Health Agency of Canada.

Among individuals with no history of depression, experiencing disruptions to healthcare access was associated with approximately double the risk of incident depression.

“Many people with COPD encountered difficulties accessing pulmonary rehabilitation services during the pandemic, which are essential for supporting both the physical and mental health of COPD patients,” said co-author Andie MacNeil, research assistant at the University of Toronto’s Factor Inwentash Faculty of Social Work (FIFSW).

“Our finding that disruptions to healthcare access were associated with incident depression highlights the reverberating consequences when healthcare is inaccessible.”

Senior author, Esme Fuller-Thomson, a Professor at FIFSW and Director of the Institute for Life Course & Aging says she hopes the study’s findings can help inform healthcare workers and social service providers about the pandemic’s impact on the mental health of people with COPD. “Future research should continue to examine depression among older adults with COPD to better understand the pandemic’s cascading impact, even in the post-COVID era,” Fuller-Thomson said.

Read more at-https://shorturl.at/lmEJV

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Government Guidelines Medical Updates Medicine & Health

Nipah virus outbreak: Top 10 symptoms of the deadly virus; prevention and treatment tips

Nipah virus outbreak: Top 10 symptoms of the deadly virus; prevention and treatment tips

While Nipah virus starts with mild symptoms like headache, muscle pain, fatigue, nausea, it may progress to deadly symptoms as the disease advances.

Amid the outbreak of Nipah virus in Kerala, the state has been taking all the precautionary measures to control the spread. So far, two people have died and at least five have been infected by the virus which has high mortality rate but is less infectious.

WHO says the Nipah virus’s fatality rate may be between 40- 75 percent. Nipah virus is a viral infection and the name ‘Nipah’ comes from a Malaysian village, where the first outbreak was reported in 1998-1999 and it has high mortality.

While Nipah virus starts with mild symptoms like headache, muscle pain, fatigue, nausea, it may progress to mental confusion, seizures and encephalitis when the virus starts affecting brain function.

What is Nipah virus?

“Nipah virus (NiV) is a zoonotic virus that can cause severe illness in humans. It is primarily transmitted from animals to humans and can also spread from human to human. The symptoms of Nipah virus infection can range from mild to severe,” says Dr Ajay Aggarwal, Director – Internal Medicine, Fortis Hospital Noida.

“Nipah virus was first identified in 1998 during an outbreak in Malaysia. Nipah virus infection can lead to severe respiratory illness and encephalitis (inflammation of the brain),” says Dr G Sneha, Consultant – General Medicine, CARE Hospitals, Banjara Hills, Hyderabad.

“Nipah virus is primarily seen in Indo Bangladesh region. In Malaysia, the source of infection was nosocomial, the source being pigs and bats who had transmitted the virus to humans. Consecutively, human to human infection is the cause of spread of the infection through droplet infection. Recently, two unnatural deaths were reported in Kozhikode, Kerela suspected to be due to a new virus outbreak in the area. It is feared that the deaths might be caused due to the Nipah virus,” says Dr Tushar Tayal, Consultant, Internal Medicine, CK Birla Hospital, Gurugram.

Symptoms of Nipah virus

Initial symptoms of Nipah virus are non-specific such as fever, headache, dizziness, myalgia, vomiting and loose stools. This may progress to brain involvement in the form of seizures and encephalitis. There may also be respiratory involvement causing respiratory failure.

“Nipah infection has very high morbidity in the form of psychiatric and neurological complications (depression, personality changes, deficits in attention, verbal, and/or visual memory) after recovery. Mortality rate of Nipah is also very high as it is majorly untraceable, and has a fatality rate of 40 to 75 percent, according to the World Health Organisation (WHO),” says Dr Tayal.

Dr Ajay Agarwal shares Nipah virus’s symptoms in detail:

1. Fever: Nipah virus infection often starts with a high fever.

2. Headache: Headaches are a common early symptom.

3. Muscle pain: Muscle aches and pain may occur, similar to flu-like symptoms.

4. Fatigue: Profound weakness and fatigue can be present.

5. Nausea: Many individuals experience nausea, sometimes accompanied by vomiting.

6. Dizziness: Some people may feel dizzy or lightheaded.

7. Mental confusion: As the disease progresses, confusion and disorientation may develop.

8. Seizures: In severe cases, individuals may experience seizures due to neurological complications.

9. Respiratory symptoms: Respiratory distress, including difficulty breathing, can occur in severe cases.

10. Coma: In the most severe cases, individuals can slip into a coma.

Dr G Sneha shares the following symptoms for Nipah virus

Fever: Nipah virus infection often begins with a high fever, typically 3 to 14 days after exposure.

Headache: Severe headaches are common.

Dizziness: Patients may experience dizziness or disorientation.

Nausea and vomiting: Gastrointestinal symptoms like nausea and vomiting may occur.

Neck rigidity: Stiff neck and muscle pain can be early signs of the infection.

Mental confusion: As the disease progresses, patients may become disoriented and develop mental confusion.

Coma: In severe cases, Nipah virus infection can lead to a coma within 24-48 hours.

“Furthermore, it’s crucial to take precautions to prevent Nipah virus transmission, as it can spread from person to person through close contact, respiratory droplets, or contact with contaminated objects or surfaces. Public health measures such as isolation, quarantine, and infection control practices are essential to prevent outbreaks of Nipah virus infection. If you suspect a Nipah virus outbreak in your area or have concerns about potential exposure, it’s essential to contact local health authorities for guidance and follow recommended preventive measures,” says Dr Agarwal.

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Treatment

Dr G Sneha says there is no specific antiviral treatment for Nipah virus infection and supportive care is the mainstay of treatment.

It may include:

1. Hospitalization: Infected individuals are usually hospitalized to receive appropriate medical care and to prevent the spread of the virus.

2. Supportive care: This includes intravenous fluids to maintain hydration, pain management, and mechanical ventilation in severe cases to assist with breathing.

3. Experimental treatments: In some cases, experimental antiviral drugs or therapies may be considered, but their effectiveness is not well established.

“Also, there are very few experimental medications such as Ribavirin and favipiravir which have shown some benefit, but the treatment remains primarily symptomatic,” says Dr Tayal.

Management

Dr G Sneha suggests Nipah virus patient should be isolated and quarantined. Here are points to remember:

1. Isolation and quarantine: Infected hould be isolated to prevent further transmission. Close contacts should be monitored and quarantined if necessary.

2. Infection control: Healthcare workers and caregivers should follow strict infection control measures to prevent the spread of the virus.

3. Preventive measures: In areas with known Nipah virus outbreaks, measures such as avoiding contact with sick animals, not consuming fruits contaminated by bat saliva or urine, and practicing good hygiene are important for prevention.

4. Vaccines: Research is ongoing, and vaccines are being developed, but as of my last update in September 2021, there was no licensed vaccine for Nipah virus.

“Hand hygiene and personal protective equipment (PPE) remain as pillars of comprehensive infection prevention. We have to remember our learning from Covid and use the same precautions that we have been following for the past few years that is hand hygiene, social distancing and usage of masks,” says Dr Tayal.

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