Tag: medical updates

COVID-19 Government Guidelines Medical Equipments Medical Updates

How cancer cells migrate to the brain? Study reveals

Post author By Pragya sharma
Post date April 5, 2023
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Treating cancer that has spread to the brain is challenging as most drugs designed to combat metastasis are either ineffective against brain metastases.

Options for treatment are limited when cancer spreads to the brain. The majority of medications made to fight metastases either cannot penetrate the blood-brain barrier or are ineffective against brain metastases.

“Understanding how cancer cells thrive or fail in the brain niche could help us develop new treatments targeting these molecular processes,” said Sofia Merajver, M.D., Ph.D., the Greater Good Breast Cancer Research Professor at the University of Michigan Rogel Cancer Center.

Merajver and colleagues used two microfluidic chips to record cancer cell migration to the brain and examine what was occurring in the blood-brain niche in order to comprehend the molecular mechanisms that affect how cancer cells pass through the blood-brain barrier. The journal Advanced NanoBiomed Research publishes the findings.

Using breast cancer cell lines, they found that Dkk-1, a cytokine released by the astrocytes, triggers the cancer cells to migrate. Dkk-1 is known to play a role in in Wnt signaling, a key signaling pathway linked to cancer progression.

“Crosstalk between brain niche cells and cancer cells allows invading cancer cells to permeate the blood-brain barrier. Reducing Dkk-1 levels near invading tumor cells might disrupt this crosstalk and prevent brain metastases,” said corresponding author Christopher R. Oliver, Ph.D., a post-doctoral fellow in the Merajver Lab.

Health spend growth dips as Covid fades

Post author By Pragya sharma
Post date April 4, 2023
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Synopsis

As a proportion of GDP, health spending has declined post-pandemic, dropping from 1.23% in 2020-21 to 1.19% in FY23 and is expected to slip further in the coming year to 1.17%. The Centre’s health spending eased from 0.41% of GDP to 0.3% of GDP over this period.

The combined health expenditure of the Centre and 17 large states is expected to log 9.6% growth in 2023-24, down sharply from an average of 16.1% between 2020-21 and 2022-23.

As a proportion of GDP, health spending has declined post-pandemic, dropping from 1.23% in 2020-21 to 1.19% in FY23 and is expected to slip further in the coming year to 1.17%.

The Centre’s health spending eased from 0.41% of GDP to 0.3% of GDP over this period.

“The increase in expenditure on health has been very small. Adjusted for inflation, economic and population growth, the health budget has declined in India,” said Dr Chandrakant Lahariya, a public health expert.

These 17 states account for 80% of the country’s overall health expenditure. The analysis excludes Tamil Nadu, union territories and north-east states, except Assam.

Reduce HDL cholesterol to combat infertility: Study

Post author By Pragya sharma
Post date March 20, 2023
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The study demonstrates that by reducing the levels of HDL cholesterol, female infertility can be addressed.

By lowering high levels of circulating cholesterol with a bacterial protein, researchers at Houston Methodist demonstrated another link between high cholesterol and female infertility in sterile mice. One in five American women of reproductive age still cannot conceive after trying for a year, so this is an encouraging development.

“We are working with a protein, called serum opacity factor, with unique characteristics,” said Corina Rosales, PhD, assistant research professor of molecular biology in medicine with the Houston Methodist Research Institute and lead author on the study. “In our experiments, serum opacity factor lowered cholesterol levels by over 40 per cent in three hours. So, this protein is quite potent.”

The results are published in the American Society for Biochemistry and Molecular Biology’s Journal of Lipid Research.

While this protein’s primary function is to increase bacterial colonization, it also alters the structure of cholesterol-carrying high-density lipoproteins, or HDLs, making it easier for the liver to dispose of the excess cholesterol that’s preventing conception. The researchers also noted that serum opacity factor’s dramatic action on HDL could be leveraged as a potential alternative to statins, which are the current gold standard for lowering cholesterol in people with atherosclerosis.

HDL, known as the “good cholesterol,” carries excess cholesterol from different tissues to the liver for breakdown, thereby bringing down cholesterol levels. However, if there is HDL dysfunction, lipid metabolism gets altered, which could then be harmful, like its counterpart LDL, or low-density lipoprotein. Often called “bad cholesterol,” LDL carries cholesterol from the liver to other tissues, with high levels of it causing accumulation and diseases.

“Both HDLs and LDLs contain a mixture of free and esterified cholesterol, and free cholesterol is known to be toxic to many tissues,” said Henry J. Pownall, PhD, professor of biochemistry in medicine at the Houston Methodist Research Institute and corresponding author on the study. “So, any dysfunction in HDL could be a risk factor for several diseases, too.”

To study HDL dysfunction, the researchers worked with preclinical mouse models that had unnaturally high levels of HDL cholesterol circulating in their bloodstream. While this made them ideal for studying atherosclerosis, Rosales observed that these mice were also wholly sterile.

“Cholesterol is the backbone of all steroidal hormones, and an orchestra of hormones is needed to have a fertile animal,” Rosales said. “We know that the ovaries are studded with receptors for HDL, so the metabolism of HDL had to play a very important role in fertility for that reason.”

As predicted, when the researchers fed the sterile mice with a lipid-lowering drug, both LDL and HDL cholesterol levels were reduced, and the animals were temporarily rescued from infertility. Motivated by these results, they turned to the bacterial protein serum opacity factor, known to be highly selective for HDL.

“Serum opacity factor is known mainly in the context of bacterial strep infections where it serves as a virulence factor. But it was also discovered that this protein only reacts to HDL and not to LDL or other lipoproteins,” Rosales said. “We hypothesized that perhaps administering serum opacity factor to these mice might help restore their fertility, as well.”

For their next set of experiments, the team engineered an adeno-associated virus to deliver the gene for serum opacity factor to the mice lacking HDL receptors that had high blood cholesterol. When the gene was expressed and the bacterial protein was produced, the animals’ HDL cholesterol significantly lowered, and their fertility was restored.

Based on these promising preclinical results, the researchers next plan is to conduct a clinical study to investigate lipid levels in women undergoing treatments for idiopathic infertility, where the underlying causes are not fully known. If these patients have high HDL levels, then the researchers say serum opacity factor may be a line of future treatment.

COVID XBB 1.16 variant: Tracker finds high cases in India, know the symptoms

Post author By Pragya sharma
Post date March 17, 2023
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A new variant of COVID XBB, namely XBB 1.16 is in news currently for driving infection cases in the country. As per an international COVID tracking platform, the highest number of sequences of this sublineage have come from India followed by Brunei, the US and Singapore, media reports have said.The prevalence of this variant of COVID virus can lead to a fresh wave of infections, reports have predicted.

The COVID positivity rates in states like Maharashtra, Karnataka and Gujarat have increased. Maharashtra, from where this new variant is believed to have originated, reported 155 COVID positive cases in a single day along with two deaths. Telangana recorded more than 100 cases on Tuesday and Wednesday combinedly. In states like Rajasthan, Madhya Pradesh, Tamil Nadu, HimachalPradesh and J&K the positivity rate is between 5% and 10%.

So far, no different symptom related to the new circulating COVID variant has been reported.The classic symptoms of COVID which give a preliminary idea about the infection are headache, muscle pain, fatigue, sore throat, runny nose and cough.Apart from the classic signs people also experience abdominal pain and discomfort, and diarrhea.

“In India, XBB.1.16 is showing a high prevalence in the states of Maharashtra and Gujarat as per covSPECTRUM. XBB 1.16 has not descended from XBB.1.5 but both have descended from XBB and more recently XBB.1,” TOI has reported quoting a top expert from India’s genome sequencing network.”XBB is currently dominating in India, and the latest uptick in cases in the country could be a result of XBB 1.16 and perhaps XBB 1.5 but a few more sample runs would clear the picture,” the expert has told the media.

The new variant is circulating at a faster pace and is already seen as a threat. Going with the previous experience of dealing with the virus, mutants of COVID virus are smarter in escaping immunity and are contagious in nature. The Omicron variant, of which the XBB 1.16 is a sub-sub variant, is notorious for its high transmission rate. Since the later months of 2021, the Omicron variant has been circulating worldwide replacing the Delta variant.As of now less is known about the course of action of the variant is not known. The rate of hospitalisation which is a serious concern during a COVID wave is also unknown. Hence people need to be careful about their own safety and also take care of those who are in the vulnerable groups.

Avoid going outdoors when you have few symptoms of the infectionAvoid going near to those who have the symptoms of the infectionAvoid going to crowded places without wearing masksDo not touch the face, especially nose, mouth and eyes, without cleaning the handsDo not touch any exposed and unclean surfaceKeep kids and older people isolated when someone in the family or in the neighbourhood has COVID.Keep the indoor air circulating. Stale air indoors is a breeding ground for coronavirus.

XBB 1.16 scare has arised amid scare around the H3N2 influenza virus which has claimed 7 lives in the country so far.H3N2 is a seasonal influenza virus caused by the viruses which are part of the viral family Orthomyxoviridae. Health experts have said that H3N2 virus does not affect the lungs and is mild in nature except for older people and those with comorbidities.COVID led to global pandemic and nationwide shut down in 2020. While things have returned to normalcy health experts are constantly warning people to stay safe from the viral infection. COVID also poses another risk of complications which are combinedly referred to as long COVID.

400 per cent increase in robotic-assisted surgeries in across Apollo hospitals in last 2 years: Healthcare group

Post author By Pragya sharma
Post date March 16, 2023
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Synopsis

According to a statement from the Apollo Hospitals, the group has expanded and introduced robotic-assisted procedures to 20-plus specialities, offering patients one of the widest and deepest tech-enabled surgical solutions in India. Hospitals under the group have conducted more than 10,000 robotic-assisted surgeries since 2011, it said.

A leading private hospital group has conducted more than 10,000 robotic-assisted surgeries since 2011, with a 400 per cent increase in such procedures in the past two years. According to a statement from the Apollo Hospitals, the group has expanded and introduced robotic-assisted procedures to 20-plus specialities, offering patients one of the widest and deepest tech-enabled surgical solutions in India.

Hospitals under the group have conducted more than 10,000 robotic-assisted surgeries since 2011, it said.

In the last two years alone, the group has witnessed over 400 per cent increase in the number of robotic-assisted procedures performed across its hospitals in India.

Robotic surgeries have seen maximum application across urological, gynaecology, oncology, orthopaedic and cardiothoracic procedures, the statement said.

Given its superior clinical precision, the use of robotics in surgeries has been instrumental in reducing overall hospital stay of patients, enabling faster recovery in most cases.

For instance, on an average, Apollo Hospitals has witnessed a reduction in its patient hospital time by up to 25 per cent in joint replacement procedures, up to 20 per cent in urological procedures and by up to a whopping 50 per cent in cardiac robotic surgeries, the statement said.

Dr Prathap Reddy, Chairman, Apollo Hospitals Group, said, “For 40 years, Apollo has pioneered the innovation in treatments to give patients the best care. Robotics is one more step in our mission to bring the best healthcare to all and we strongly believe that it will form the backbone of our country’s medical infrastructure in the decade to come.”

In the first two months of 2023, Apollo Hospitals performed more than 450 robotic surgeries in India and expects this number to increase significantly through the year.

Morality risk for people with dementia rises after hurricane exposure

Post author By Pragya sharma
Post date March 15, 2023
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It is observed that with disruption in normal routine, such as access to caregiving, changes in living environment, loss in access to medications, and change in daily routines, the mortality risk for dementia patients see a significant rise.

Prior hurricane studies have found general increases in fatality, but nothing is known about how death may differ among older adults living with dementia.

Their increased risk could be due to disruption of normal routine, such as access to caregiving, changes in living environment, loss in access to medications, and change in daily routines, said study first author Sue Anne Bell, assistant professor at the U-M School of Nursing.

The analysis focused on risk for mortality among people with dementia, rather than actual increases in mortality. The findings don’t give a precise number of deaths due to hurricane effects.

Bell and colleagues examined counties in U.S. states affected by Hurricanes Irma, Harvey and Florence in the year before and after the storm. There were 54,340 deaths among the study population of 346,171.

Key findings include:

Risk of mortality was highest in those aged 85 and older, with a 9% increase in risk of death compared to adults over 85 without dementia. Older adults who are enrolled in both Medicare and Medicaid had an 11% increased risk for mortality. Among people with dementia who moved a year after the storm, the risks for mortality remained whether they moved or not. The percentage of mortality attributed to exposure among people with dementia ranged from 10.9% for Harvey to 6.2% for Irma. Mortality peaked 3-6 months after hurricanes Irma and Harvey, suggesting the increase in mortality was due to factors other than the immediate harms of the storm, such as lack of health care access and changes in normal routines. Why the impact on dementia patients matters

The Population Reference Bureau estimates that more than 7 million people aged 65 or older had dementia in 2020, Bell said. If current demographic and health trends continue, more than 9 million Americans could have dementia by 2030 and nearly 12 million by 2040. As climate change worsens, disasters will increase along with the numbers of people with dementia.

“The important message is that older adults with dementia have unique needs, most notably that during a disaster, they are almost entirely dependent on caregivers due to their lack of awareness of the crisis,” Bell said. “I think if anything, there is new attention to the needs of older adults during a disaster, and this study is one of an emerging body of evidence that is working to better support the needs of older adults before, during and after disasters.

Next steps in disaster research and dementia

“There is so much more that needs to be studied here that could help inform us about being ready for disasters,” Bell said. “Studying how caregivers have prepared, whether people evacuated, what type of response capabilities their community had–would potentially influence the impact of the disaster on this group of older adults.”

Bell hopes these findings raise awareness about the special needs of people living with dementia during disasters and call for an integrated approach to preparedness and response that includes local, state and federal responders, healthcare regulators, and policy makers.

Cancer treatment: Artificial human skin now part of new skin cancer therapy

Post author By Pragya sharma
Post date March 13, 2023
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Artificial skin is the closest we get to real human skin and a new study has been successful in stopping invasive growth in a skin cancer model by utilising synthetic human skin.

A research team from the University of Copenhagen has been successful in stopping invasive growth in a skin cancer model by utilising synthetic human skin.

The study, which examines what exactly occurs when a cell transforms into a cancer cell, has been published in Science Signaling.

“We have been studying one of the cells’ signalling pathways, the so-called TGF beta pathway. This pathway plays a critical role in the cell’s communication with its surroundings, and it controls e.g., cell growth and cell division. If these mechanisms are damaged, the cell may turn into a cancer cell and invade the surrounding tissue,” explains Professor and Team Lead Hans Wandall from the Department of Cellular and Molecular Medicine at the University of Copenhagen.

Under normal circumstances, your skin cells will not just start to invade the hypodermis and wreak havoc. Instead, they will produce a new layer of skin. But when cancer cells emerge, the cells no longer respect the boundaries between skin layers, and they start to invade each other. This is called invasive growth.

Hans Wandall and his colleagues have been studying the TGF beta pathway and applied methods for blocking invasive growth and thus curbing the invasive growth in skin cancer.

“We already have various drugs that can block these signalling pathways and which may be used in tests. We have used some of them in this study,” explains Associate Professor and co-author of the study Sally Dabelsteen from the School of Dentistry.

Hans Wandall and Sally Dabelsteen have worked together with Dr Zilu Ye and Professor Jesper V. Olsen from the Novo Nordisk Foundation Center for Protein Research at the Faculty of Health and Medical Sciences.

“Some of these drugs have already been tested on humans, and some are in the process of being tested in connection with other types of cancer. They could also be tested on skin cancer specifically,” she says.

Artificial skin is the closest we get to real human skin

The artificial skin used by the researchers in the new study consists of artificial, genetically manipulated human skin cells. Skin cells are produced on subcutaneous tissue made of collagen. This makes the cells grow in layers, just like real human skin.

Unlike mice models, the skin model, which is another word for artificial skin, allows researchers to introduce artificial genetic changes relatively quickly, which provides insight into the systems that support skin development and renewal.

This way they are also able to reproduce and follow the development of other skin disorders, not just skin cancer.

“By using artificial human skin we are past the potentially problematic obstacle of whether results from tests on mice models can be transferred to human tissue. Previously, we used mice models in most studies of this kind. Instead, we can now conclude that these substances probably are not harmful and could work in practice, because the artificial skin means that we are closer to human reality,” says Hans Wandall.

The artificial skin used by the researchers resembles the skin used to test cosmetics in the EU, which banned animal testing in 2004. However, artificial skin does not allow the researchers to test the effect of a drug on the entire organism, Hans Wandall points out. Skin models like the one used here have been used by cosmetics companies since the mid-1980s.

“We can study the effect focussing on the individual organ — the skin — and then we reap experiences with regard to how molecules work, while we seek to determine whether they damage the structure of the skin and the healthy skin cells,” he says.

H3N2 influenza in India; tips to prevent infection while playing Holi

Post author By Pragya sharma
Post date March 7, 2023
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Ahead of Holi, a new virus H3N2 has become a cause of concern in India with its rapid spread. Here are precautions you must follow during the festival of colours to prevent infection.

Holi celebrations have already begun in many parts of the country and the preparations for festival special food menu from gujiya, malpua, kheer to dahi vada as well as shopping for gulal, abeer, pichkari, are on in full swing. While Holi is all about keeping your everyday stress aside and soaking in the festive and colourful spirit of the festival, a new virus H3N2 has become a cause of concern in India with its rapid spread. It is thus important to not only take care of your skin and hair during the festival, but also follow social distancing measures to prevent from the infections. If you suffer from any of the symptoms from fever, respiratory symptoms like cough and runny nose, or body aches, nausea, vomiting, or diarrhoea, you must consult your doctor and start medication.

“Skin and hair issues in the festival of colours are not going to be the only concern this year as a new virus H3N2 has been spreading all over India, due to the rapid shift in weather from cold to warmer temperatures. The increase in the number of patients complaining of viral infections and chest congestion demonstrates how seasonal change is having a negative influence on people’s health. Pollution is also playing a significant influence in increasing the number of patients affected by viral diseases. With Holi coming into the picture, the elderly, children, and pregnant women are the most vulnerable to infection. As a result, they must exercise extreme caution while celebrating Holi. Apart from asthmatic patients, there are many additional individuals who have serious lung infections and are having difficulty breathing they need to be extra careful as they can inhale the colours which can cause serious harm to their health,” says Dr. SK Chhabra, Head of Department – Pulmonary, Primus Hospital, New Delhi.

H3N2 influenza in India; tips to prevent infection while playing Holi

“During Holi, even small respiratory problems must be reported to a pulmonologist or a physician to avoid the condition from worsening. Similar to seasonal flu virus H3N2, other viruses are also in circulation, including H1N1 and adenoviruses and these infections can cause fever, respiratory symptoms like cough and runny nose, as well as other symptoms including body aches, nausea, vomiting, or diarrhoea,” adds Dr. SK Chhabra.

Keeping skin and hair concerns in mind Dr. Navya Handa, Consultant Dermatologist and Cosmetologist at Primus Super Specialty Hospital suggests some useful tips such as a few hours before playing Holi, you should apply oil to your body and hair – you may use coconut or almond, or olive oil. “In addition, you should apply a good sunscreen on your face and any exposed skin. It hydrates the skin and reduces the number of colours absorbed by the skin and hair. Tie your hair instead of keeping them open so that there is less space for chemicals to get to the scalp,” says Dr Handa.

PRECAUTIONS TO FOLLOW DURING HOLI FOR PREVENTING FLU SPREAD

These measures will help prevent the flu and limit its spread:

1. Wash your hands frequently: Always and extensively clean your hands with soap and water, or an alcohol-based hand sanitizer if neither is available.

2. Cover your coughs and sneezes: Use a tissue or your elbow to sneeze or cough into if you must expose others to your germs. Do a quick handwashing.

3. Don’t touch your face unnecessarily: Don’t touch your face too much; that includes your eyes, nose, and mouth.

4. Clean surfaces: Keep frequently touched surfaces clean to avoid picking up the virus from them and spreading it to your body.

5. Avoid crowd: If at all possible, avoid congested areas. Keep your distance from those who are ill. You should avoid swine barns at seasonal fairs and elsewhere if you are at high risk of problems from the flu because of your age (younger than 5 or 65 or older), your health (pregnant or have a chronic illness like asthma).

ASG Eye Hospitals takes operation control of Vasan Eye Care

Post author By Pragya sharma
Post date March 6, 2023
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Synopsis

Investors of ASG Eye Hospitals include Foundation Holdings, General Atlantic, and Kedaara Capital. The investors would work closely with the teams of ASG and Vasan to realise the vision of becoming the leading eye care franchise in India by providing high quality eye care services. Foundation Holdings Managing Director Aakash Sachdev, who is also the ASG Eye Hospitals Director, said the strategic acquisition marks an exciting time for ASG and Vasan and a historic milestone in the eye care sector.

Rajasthan-headquartered ASG Eye Hospitals has commenced steps to take operational control of Vasan Eye Care following the completion of all formalities and transfer of ownership, the eye care provider said on Saturday. Post the merger, Vasan Eye Care would remain as an independent eye care brand, ASG Eye Hospitals said.

On February 3, National Company Law Tribunal approved the resolution plan of ASG Hospitals to acquire Vasan Healthcare Pvt Ltd with a bid value of Rs 526 crore with 98 per cent of the votes received from the Committee of Creditors.

The successful completion of acquisition marks a significant milestone in ASG Eye Hospitals’ journey to expand into new and underserved markets in India and make quality eye care accessible to all,” ASG Eye Hospitals said.

Commenting on the development, ASG Eye Hospital Pvt Ltd Chairman and Managing Director Arun Singhvi said: “Post this strategic acquisition, we are proud to expand our network presence in South India. Vasan Eye Care is a valued and respected name in eye care and will continue as an independent brand.”
ASG Eye Hospitals, based in Jodhpur, has served over 7.5 million people through its 54 state-of-the-art speciality eye care hospitals across 17 states in the country. It has a presence abroad in Uganda and Nepal as well.

With the addition of Vasan Eye Care, the network of ASG Eye Hospitals would increase to over 150 across India with presence in 21 states, it said.
The strategic acquisition would strengthen ASG’s position in the healthcare industry and enhance its market presence, ASG Eye Hospitals said.

“We are delighted to welcome the Vasan team to the ASG family to join our mission to enhance the delivery of quality eye care for all and improve the quality of life across India.” Singhvi said.

“We look forward to working closely with all stakeholders in the Vasan ecosystem to ensure a seamless transition as we continue to deliver unparalleled patient care,” he said.

Investors of ASG Eye Hospitals include Foundation Holdings, General Atlantic, and Kedaara Capital. The investors would work closely with the teams of ASG and Vasan to realise the vision of becoming the leading eye care franchise in India by providing high quality eye care services.

Foundation Holdings Managing Director Aakash Sachdev, who is also the ASG Eye Hospitals Director, said the strategic acquisition marks an exciting time for ASG and Vasan and a historic milestone in the eye care sector.

The Vasan acquisition will be a perfect geographic fit with ASG and a unique opportunity to establish ASG as a world-class healthcare delivery platform with a scaled South India presence and pan-India reach,” he said.

Vasan Eye Care network is a premier institution of eye care hospitals in the country and has been serving over six million patients every year. It has over 100 super speciality eye care hospitals in its network, Vasan Eye Care said in its website.

Influenza (flu) vs Covid: Symptoms, differences and similarities

Post author By Pragya sharma
Post date March 3, 2023
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Despite the fact that COVID-19 and influenza (flu) are both contagious respiratory illnesses, they are caused by separate viruses. COVID-19 is induced by contact with a coronavirus (SARS-CoV-2) that was discovered in 2019. Flu is caused by infection with a flu virus (influenza viruses).

From no signs (asymptomatic) to severe symptoms, COVID-19 and the flu can both have a range of symptoms. The flu and COVID-19 both commonly exhibit these symptoms:

Experiencing chills or feeling feverish, Cough, Respiratory issues or shortness of breath, Fatigue, Sore throat, Runny or congested nostrils, Headache, Vomiting, Diarrhea (more common in children with flu, but can occur in any age with COVID-19), Taste or scent alteration or loss, though this occurs more frequently with COVID-19.

How does it spread?

Similarities:

People who are close to or in direct contact with one another are more likely to contract COVID-19 or the flu. Both are primarily transmitted by virus-containing large and small particles that are released when COVID-19 or flu patients cough, sneeze, or talk. Majority of transmission occurs through the inhalation of large and tiny droplets, it is still possible for someone to become infected by touching another person who has the virus

Differences:

Superspreading episodes for COVID-19 have been found to be higher than those for flu. This implies that the virus that causes COVID-19 can rapidly and easily spread to a large number of people and cause ongoing spreading among people over time.
People without symptoms, people with very mild symptoms, and people who never experience symptoms can all transmit the virus that causes COVID-19 to others (asymptomatic people).

Similarities: For both COVID-19 and the flu, it may take one or more days for a person to start showing signs after contracting the infection. The virus that causes COVID-19 can be contracted even if no signs are present. Flu viruses can also infect people even when they show no signs.

Differences: Compared to the flu, COVID-19 patients may encounter symptoms later in the course of the illness where as an individual typically experiences symptoms one to four days after infection in flu.

Differences:
Compared to the flu, COVID-19 may render an individual more contagious for a prolonged period of time.

Flu
Before showing symptoms, people who have the flu virus are possibly contagious for about one day. However, it is thought that the majority of those who transmit the flu virus infection are already exhibiting flu-like symptoms.
Although some individuals may continue to be contagious for a little longer periods, older children and adults with the flu appear to be most contagious during the first 3–4 days of their illness.

COVID-19
The COVID-19 virus can start spreading between two and three days before symptoms appear, but it reaches its highest infectiousness the day before symptoms start. The COVID-19 virus can also propagate among people even when they are asymptomatic. People are typically deemed contagious for eight days after the onset of their symptoms.

Similarities: COVID-19 and the flu both have the potential to cause serious sickness and complications. Those at higher risk comprise of older people, individuals with particular underlying medical problems, pregnant women.

Differences:

Even healthy individuals can develop a severe COVID-19 illness that requires hospitalisation and results in death. Some COVID-19 patients may go on to acquire multisystem inflammatory syndrome or post-COVID conditions (MIS)

Certified treatments

Similarities:

People who are more likely to develop complications or who have been admitted to the hospital with COVID-19 or the flu should receive the proposed treatments and supportive care to assist with symptom relief and complications.

Differences:

Flu
Guidelines for treating COVID-19 have been established by the National Institutes of Health (NIH), and they are frequently updated as new information about potential treatments becomes available. Antiviral therapy is included here for individuals who aren’t admitted but are at higher risk.

COVID-19
Guidelines for treating COVID-19 have been established by the National Institutes of Health (NIH), and they are frequently updated as new information about potential treatments becomes accessible. This covers both antiviral treatment for patients hospitalised with severe COVID-19 and antiviral treatment for non-hospitalized individuals at higher risk for the virus. People who are more likely to develop severe COVID-19 should get help as soon as their first symptoms appear.